首页 | 本学科首页   官方微博 | 高级检索  
     检索      


A Convenient Synthesis and Pharmacological Activity of Novel Annelated Pyrimidine Derivatives
Authors:A A Aly
Abstract:Simple and convenient synthesis for a series of 2,3‐diglycosylpyrimidine 4 , pyrazolo3,4‐d]pyrimidine 8 , ditetrazolo1,5‐a;1′,5′‐c]pyrimidine 9 , 2,9a,10‐triazaanthracene 12 , thieno2,3‐d]pyrimidine 14 , 1,3,5,7‐tetraazafluorene‐8‐one 15 , 1,3,5‐triazafluorene‐8‐one 16 , 1,3‐diazafluorene 21a,b derivatives have been synthesized via a sequence of heterocyclization reactions of suitably functionalized 6‐5‐(4‐bromophenyl)ox‐azol‐4‐yl]‐4‐oxo‐2‐thioxo‐1,2,3,4‐tetrahydropyrimidine‐5‐carbonitrile ( 2 ) with different electrophiles and nucleophiles. The new compounds were prepared with the objective to study their pharmacological properties.
Keywords:2‐Methylsulfanylpyrimidine  Pyrazolo[3  4‐d]pyrimidine  Thieno[2  3‐d]pyrimidine  Azafluorenone
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号