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Nucleophilic aromatic substitution of methyl 3‐nitropyridine‐4‐carboxylate |
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| Authors: | Jarle Holt Freddy Tjoss Jan M Bakke Anne Fiksdahl |
| Institution: | Jarle Holt,Freddy Tjosås,Jan M. Bakke,Anne Fiksdahl |
| Abstract: | The nitro group of methyl 3‐nitropyridine‐4‐carboxylate ( 1 ) has successfully been replaced by nitrogen, oxygen and sulphur nucleophiles by nucleophilic aromatic substitution to give the 3‐azido, 3‐methoxy, 3‐phenoxy and 3‐thiophenoxypyridine‐4‐carboxylates ( 2a — d ). |
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