Benzylic oxidation catalyzed by dirhodium(II,III) caprolactamate |
| |
| Authors: | Catino Arthur J Nichols Jason M Choi Hojae Gottipamula Sidhartha Doyle Michael P |
| |
| Affiliation: | Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, USA. |
| |
| Abstract: | [reaction: see text] Dirhodium caprolactamate [Rh2(cap)4] is an effective catalyst for benzylic oxidation with tert-butyl hydroperoxide (TBHP) under mild conditions. Sodium bicarbonate is the optimal base additive for substrate conversion. Benzylic carbonyl compounds are readily obtained, and a formal synthesis of palmarumycin CP2 using this methodology is described. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
