Trace and major elements in serum of patients with chronic myelogenous leukemia |
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| Authors: | C. G. L. Canellas S. M. F. Carvalho E. F. O. De Jesus M. J. Anjos R. T. Lopes |
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| Affiliation: | (1) Federal University of Rio de Janeiro/COPPE, Nuclear Instrumentation Laboratory, P.O. Box 68509, Rio de Janeiro, Brazil;(2) Foundation Institute of Hematology, Rio de Janeiro, Brazil;(3) Federal University of Rio de Janeiro/COPPE, Nuclear Instrumentation Laboratory; Physics Institute, UERJ, P.O. Box 68509, Rio de Janeiro, Brazil; Rio de Janeiro, Brazil;(4) Federal University of Rio de Janeiro/COPPE, Nuclear Instrumentation Laboratory; Physics Institute, UERJ, P.O. Box 68509, Rio de Janeiro, Brazil; Rio de Janeiro, Brazil;(5) Federal University of Rio de Janeiro/COPPE, Nuclear Instrumentation Laboratory, P.O. Box 68509, Rio de Janeiro, Brazil |
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| Abstract: | Summary Major and trace elements were determined in serum of patients with chronic myelogenous leukemia (CML) using total reflection X-ray fluorescence induced by synchrotron radiation (SRTXRF). CML affects 1 to 2 people per 100,000 and accounts for 7-20% cases of leukemia. It was possible to determine the concentrations of the following elements: P, S, Cl, K, Ca, Cr, Mn, Fe, Ni, Cu, Zn, Br and Rb. Using analysis of variance (ANOVA) it was observed that the contents of the P, S, Ca, Cr, Mn, Fe, Cu and Rb elements differed significantly at a = 0.05 between groups of healthy subjects and CML patients and also genders (males and females). |
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