| 纳米金生物探针及其应用 |
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| 引用本文： | 王楠,徐淑坤,王文星. 纳米金生物探针及其应用[J]. 化学进展, 2007, 19(2): 408-413 |
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| 作者姓名： | 王楠 徐淑坤 王文星 |
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| 作者单位： | 东北大学化学系,沈阳,110004;东北大学化学系,沈阳,110004;东北大学化学系,沈阳,110004 |
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| 基金项目： | 高等学校博士学科点专项科研项目 |
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| 摘 要： | 纳米技术与生物技术的融合,使纳米生物技术获得了很多重要的进展.纳米金作为研究较早的一种纳米材料,其在纳米生物探针方面的应用是最近几年较为活跃的研究方向.本文评述了近年来纳米金探针在生物分析中的应用及进展,阐述了纳米金与生物大分子作用的机理,介绍了纳米金探针在核酸分析、免疫分析、单细胞分析和靶向药物载体4个方面应用的最新进展,并对其未来的发展方向进行了展望.
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| 关 键 词： | 纳米金 探针 生物分析 |
| 文章编号： | 1005-281X（2007）02/3-0408-06 |
| 收稿时间： | 2006-04-01 |
| 修稿时间： | 2006-08-01 |
Nano-Gold Bio-Probe and Its Applications |
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| Wang Nan,Xu Shukun,Wang Wenxing. Nano-Gold Bio-Probe and Its Applications[J]. Progress in Chemistry, 2007, 19(2): 408-413 |
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| Authors: | Wang Nan Xu Shukun Wang Wenxing |
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| Affiliation: | Department of Chemistry, Northeastern University, Shenyang 110004, China |
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| Abstract: | In recent years, the combination of nanotechnology and biotechnology made great important progress in nano biotechnology. As a kind of earlier nano materials, nano-gold bio-probe has became a hot area. A review with 46 references is presented On the new development of nano-gold bio-probe in bio-analytical chemistry by introducing the reaction mechanism between nanogold and biological macromolecules and their applications. Four aspects are reviewed involving nucleic acid analysis, immuno-analysis, single cell analysis and carrier of target medicine. The tendency of nano-gold probe in bio-analytical chemistry is also discussed. |
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| Keywords: | nano-gold probe bio-analytical chemistry |
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