Synthetic Studies of an Analogue of HIV-1 Protease Inhibitors of Didemnaketals:Construction of the C1-C8 Intermediate |
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| Authors: | Ping Zhen WANG Yan Xing JIA Yong Qiang TU Bin WU |
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| Abstract: | A convenient and stereoseleetive approach to the synthesis of (3S. 4R. 6S)-2-oxo-3.4- dihydroxy-6-methyl-octanate derivative,a key intermediate for the synthesis of IIIV-1 proteaseinhibitor of didemnaketals analogue,has been developed successfully from L-(-)-menthone. |
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| Keywords: | Didemnaketals.2-oxo-3. 4-dihydroxy-6-methyl-octanate. steroselective synthesis. |
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