Screening for inducers of kinase degradation |
| |
| Authors: | Neckers Len |
| |
| Institution: | Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, 9610 Medical Center Drive, Rockville, MD 20850, USA. |
| |
| Abstract: | Targeted small molecule-induced protein degradation is a promising approach to inhibit signaling within kinase cascades. In this issue, researchers describe a simple assay for the rapid, high-throughput identification of novel agents that promote degradation of the kinases Her2 and EGFR. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
