PCEP enhances IgA mucosal immune responses in mice following different immunization routes with influenza virus antigens |
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| Authors: | Nelson F Eng Srinivas Garlapati Volker Gerdts Lorne A Babiuk and George K Mutwiri |
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| Institution: | (1) Vaccine & Infectious Disease Organization/International Vaccine Center, University of Saskatchewan, 120 Veterinary Road, S7N 5E3 Saskatoon, Saskatchewan, Canada;(2) University of Alberta, 3-7 University Hall, T6G 2J9 Edmonton, Alberta, Canada |
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| Abstract: | Background We previously demonstrated that polyphosphazenes, particularly PCEP, enhance immune responses in mice immunized subcutaneously
and intranasally. The objective of the present study was to investigate the efficacy of polyphosphazenes as adjuvants when
delivered through different routes of vaccine administration. |
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