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Benzoxazoles as transthyretin amyloid fibril inhibitors: synthesis,evaluation, and mechanism of action
Authors:Razavi Hossein  Palaninathan Satheesh K  Powers Evan T  Wiseman R Luke  Purkey Hans E  Mohamedmohaideen Nilofar N  Deechongkit Songpon  Chiang Kyle P  Dendle Maria T A  Sacchettini James C  Kelly Jeffery W
Affiliation:Department of Chemistry, The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Abstract:
Keywords:aggregation  bioorganic chemistry  drug design  inhibitors  structure–activity relationships
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