C-F Bond Formation for the Synthesis of Aryl Fluorides |
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| Authors: | Furuya Takeru Klein Johannes E M N Ritter Tobias |
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| Institution: | Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA. |
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| Abstract: | A selection of carbon-fluorine bond-forming reactions is presented with particular focus on transition metal-mediated fluorination. A brief summary of conventional fluorination reactions is followed by a discussion of fluorination reactions mediated by palladium and silver. Investigations into the mechanism as well as the conceptual difficulty associated with transition metal-mediated carbon-fluorine bond formation are presented. |
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