Interaction of 5-fluorouracil with sodium carboxymethylcellulose |
| |
| Authors: | K Nishida Y Ando M Enomoto |
| |
| Institution: | (1) Present address: Department of Industrial Chemistry, Tokyo University of Agriculture and Technology, Tokyo, Japan |
| |
| Abstract: | The interaction of an anticancer drug, 5-fluorouracil with sodium carboxymethylcellulose in aqueous solution was studied with a spectral method and viscosity measurement. From the binding data, the standard molar change in enthalpy, entropy and the number of binding sites on polymer were calculated. The standard molar change of enthalpy of 5-fluorouracil is about — 7 Kcal/mol with sodium carboxymethylcellulose. The enthalpy change is a considerably greater. |
| |
| Keywords: | 5-fluorouracil Sodium carboxymethylcellulose Interaction Enthalpy Viscosity |
| 本文献已被 SpringerLink 等数据库收录！ |
