Department of Applied Chemistry, Faculty of Science, Science University of Tokyo, Kagurazaka, Shinjuku-ku, Tokyo 162, Japan
Abstract:
Tetrabutylammonium fluoride in N, N-dimethylformamide (DMF) is an effective alternative to the piperidine reagent for the removal of 9-fluorenylmethyloxycarbonyl (Fmoc) group in the solid phase peptide synthesis.