Porous biosorbents on the basis of methacrylic acid and triallylisocyanurate

Novel granular biosorbents of cellular structure were obtained by suspension copolymerization of methacrylic acid and a trivinylic cross-linking agent, triallylisocyanurate. The main advantage of these sorbents in comparison with the conventional ones is the absence of a dense shell on the surface. The cellular structure is characterized by the negative radius of curvature of the polymer phase surface. Investigations into acidic properties of carboxyl groups in the series of copolymers with various concentration of the cross-linking agent (from 1 to 20 mol.%) revealed no cooperativity of ionization of carboxyl groups typical of conformationally stable cross-linked polyelectrolytes. The regularities of reversible binding of model proteins to the copolymers of methacrylic acid with triallylisocyanurate were studied; the possibility of chromatographic separation of proteins using sorption and reversible desorption on the obtained cation-exchange resins was demonstrated.