Metabolic Effects of HAY's Diet |
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| Authors: | K D Wutzke W E Heine D Köster J Muscheites M Mix C Mohr |
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| Institution: | 1. University of Rostock, Department of Paediatrics , Rostock, Germany;2. University of Rostock, Children's Hospital, Research Laboratory , Rembrandtstr. 16/17, 18055, Rostock, Germany Phone: +49-381-4947135 Fax: +49-381-4947135 E-mail: klaus-dieter.wutzke@med.uni-rostock.de;3. University of Rostock, Department of Paediatrics , Rostock, Germany;4. University of Rostock, Department of Internal Medicine , Rostock, Germany |
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| Abstract: | Abstract The aim of the study was, to evaluate the metabolic effect of HAY's diet on protein turnover, fat oxidation, respiratory quotient, body fat and weight loss. Twelve healthy adults received an individually regular diet and thereafter a corresponding isocaloric and isonitrogenous 10-day HAY-diet. Protein turnover and 13C-fat oxidation were investigated after administration of 15N]glycine and an U-13C]algae lipid mixture. The 15N and 13C enrichment in urine and breath were measured by isotope ratio mass spectrometry. The respiratory quotient was measured by indirect calorimetry. Body fat, total body water and lean body mass were estimated by bio-electric impedance analysis. HAY's diet led to a significantly higher 13C-fat oxidation (15.4 vs. 22.0% P < 0.01), corresponding to a lower respiratory quotient (0.88 vs. 0.81; P < 0.01), whereas the protein turnover remained constant in both diets (3.06 vs. 3.05 g/kg/day). HAY's diet did not reduce total body water, lean body mass, body fat and body weight (72.2 vs. 71.4 kg). |
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| Keywords: | carbon 13 fat oxidation HAY's diet respiratory quotient weight loss whole-body protein turnover |
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