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Catalytic Tritiation of Cardiac Glycosides
Authors:D Murawski  G Lindig  U Zelck  K Repke
Abstract:With tritium gas acting upon the solutions of cardio-active unsaturated steroid lactones in the presence of catalysts, there results a mixture of labelled parent compounds and labelled dihydroderivates. The influence of various catalysts upon transformation speed and radiochemical yield ratio of exchange and addition products has been investigated. A method rendering possible preparative separation of the obtained cardenolides and cardanolides labelled with tritium is described.
Keywords:catalytic exchange  cardiac glycosides  labelled compounds  production  trituim
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