Stereospecific Olefin Synthesis via Lithium Vinylcuprates |
| |
Authors: | F Nf P Degen |
| |
Institution: | F. Näf,P. Degen |
| |
Abstract: | The conjugate addition of cis- or trans-1-alkenyl-cuprolithium complexes (R? CH?CH? )2CuLi · Xn 1 R ? alkyl, X ? ligands such as ether, tetrahydrofuran, (CH3O)3P and (n-Bu)3P. Physical studies to determine the structure of these copper reagents are in progress, see footnote 20 of reference 1]. to α, β-unsaturated carbonyl compounds was found to occur with high retention of double bond geometry, affording isomerically pure cis- or trans-γ, δ-ethylenic carbonyl compounds. The same 1-alkenylcuprates also react stereospecifically with alkyl halides to give isomerically pure cis- or trans-olefins. |
| |
Keywords: | |
|
|