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Asymmetric synthesis of a chroman derivative (vitamin e precursor)
Authors:Yoji Sakito  Gohfu Suzukamo
Institution:Central Research Laboratory, Sumitomo Chemical Co., Ltd. Takatsuki, Osaka 569, Japan
Abstract:Chromanmethanol 2, a chiral intermediate for the synthesis of α-tocopherol 1, is prepared from α-hydroxy aldehyde 5, which is obtained by an asymmetric synthesis in over 95% ee.
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