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New benzyne approach to the synthesis of dehydroaporphines, 4,5-dioxoaporphines and aristolactams
Authors:Luis Casteda  Enrique Guitián  José M Saá  Rafael Suau
Institution:Departamento de Química Orgánica e Instituto de Productos Naturales Orgánicos (Sección Alcaloides) del C.S.I.C. Santiago de Compostela Spain
Abstract:A new strategy for the synthesis of some aporphinoid alkaloids is described. It is based on the intermolecular Diels-Alder cyclization between benzyne and an appropriate methylene isoquinoline derivative.
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