Metal ions as selective triggers for removing oligodeoxynucleotide phosphotriester protecting groups |
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| Authors: | Y Stabinsky RT Sakata MH Caruthers |
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| Institution: | Department of Chemistry, University of Colorado, Boulder, Colorado 80309 U.S.A. |
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| Abstract: | The o-bromophenyl group was successfully tested as a phosphotriester protecting group for internucleotide bonds. This protecting group can be readily and selectively removed using various transition metal salts in aqueous pyridine. |
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