A direct transformation of bicyclic keto esters to <span class="math"><math><mtext>N</mtext></math></span>-formimidoyl thienamycin期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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A direct transformation of bicyclic keto esters to $N$ -formimidoyl thienamycin

Authors:	I Shinkai RA Reamer FW Hartner T Liu M Sletzinger

Institution:	Department of Process Research Merck Sharp & Dohme Research Laboratories Rahway, New Jersey 07065, U.S.A.

Abstract:	A convenient direct transformation of $p$ -nitrobenzyl 6-(1′-hydroxyethyl)-1-azabicyclo-(3.2.0)heptane-3,7-dione-2-carboxylate to $N$ -formimidoyl thienamycin utilizing the silylated derivative of $N$ -formimidoyl cysteamine is described.

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