Efficient Synthesis of 3,5,6,7-Tetrahydro-4H-cyclopenta[4,5] thieno[2,3-d]Pyrimidin-4-ones |
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Authors: | LIU Ming-guo ZHONG Ying DING Ming-wu |
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Institution: | a Key Laboratory of Pesticide &; Chemical Biology of Ministry of Education, Central China Normal University, Wuhan 430079, P. R. China; b Hubei Key Laboratory of Natural Products Research and Development, China Three Gorges University, Yichang 443002, P. R. China |
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Abstract: | The title compounds 3,5,6,7-tetrahydro-4H-cyclopenta4,5]thieno2,3-d]pyrimidin-4-ones(6) were synthesized by base catalytic reactions of secondary amines with carbodiimides 4,which were obtained from the aza-Wittig reaction of iminophosphoranes(3) with aromatic isoeyanates. |
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Keywords: | Cyclopenta[4 5]thieno[2 3-d]pyrimidin-4-one Aza-Wittig reaction Carbodiimide Isocyanate |
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