| 脱氢醋酸与氨的反应 |
| |
| 引用本文： | 陈伟兴,冯骏材,傅和亮,沙坚,张林.脱氢醋酸与氨的反应[J].高等学校化学学报,1988,9(9):969. |
| |
| 作者姓名： | 陈伟兴 冯骏材 傅和亮 沙坚 张林 |
| |
| 作者单位： | 南京大学化学系 |
| |
| 摘 要： | 脱氢醋酸(1)与氨反应生成2,6-二甲基-4-羟基吡啶(2)1]。IguChi等2]曾用纸层析法定性地研究了这反应的过程。为进一步了解(1)与氨反应的历程及影响反应的因素,我们用HPLC研究了在不同反应条件下得到的中间体和产物,研究了相互转变关系,并进行了分离和鉴定。初步提出了该反应的可能历程。
|
| 关 键 词： | 脱氢醋酸 2 6-二甲基-4-羟基吡啶 |
| 收稿时间： | 1987-03-31 |
Study on the Reaction of Dehydroacetic acid with Ammonia |
| |
| Chen Weixing,Feng Juncai,Fu Heliang,Sha Jian,Zhang Lin.Study on the Reaction of Dehydroacetic acid with Ammonia[J].Chemical Research In Chinese Universities,1988,9(9):969. |
| |
| Authors: | Chen Weixing Feng Juncai Fu Heliang Sha Jian Zhang Lin |
| |
| Institution: | Department of Chemistry, Nanjing University, Nanjing |
| |
| Abstract: | In this work, the reaction of dehydroacetic acid (1) with aqueous ammoniahas been further studied by means of HPLC. In this reaction lutidone (2), lutidonecarboxylic acid (4) and 2,6-dimethyl-4-aminopyridine (6) have been separated or prepared.DHA-imide (3) (3-iminoethyl-4-hydroxy-6-methyl-2-pyrone) is the intermediate which gives various compounds under different conditions. The mechanism of this reaction is discussed.The structures of compounds have beeen characterized by IR, 1HNMR and MS spectra. |
| |
| Keywords: | Dehydroacetic acid 2 6-dimethyl-4-hydroxypyridine |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《高等学校化学学报》浏览原始摘要信息 |
| 点击此处可从《高等学校化学学报》下载免费的PDF全文 |
|
