| Regioselective addtion of 5-amino-3-benzylthio-l,2,4-triazole and its analogues with aryl isocyanates |
| |
| 作者姓名： | LU Rong-Jian QIAN Bao-Ying DENG Hai-Yan YANG Hua-ZhengNational Key Laboratory of Elemento-Organic Chemistry Institute of Elemento-Organic Chemistry Nankai University Tianjin China |
| |
| 作者单位： | LU，Rong-Jian QIAN，Bao-Ying DENG，Hai-Yan YANG，Hua-ZhengNational Key Laboratory of Elemento-Organic Chemistry，Institute of Elemento-Organic Chemistry，Nankai University，Tianjin 300071，China |
| |
| 基金项目： | Project supported by the National Natural Science Foundation of China and the Natural Science Foundation of Tianjin. |
| |
| 摘 要： | The orientation of the addition of 5-amino-3-benzylthio-1,2,4-triazole and its analogues (pyrazole) (1) with the aryl isocyanate can be directed by controlling the reaction temperature and one of the product, 5-amino-1-arylaminocarbonyl-3-benzylthio-1,2,4-triazole (pyrazole) (2), can rearrange at 170C to another product, 5-arylureylene-3-benzylthio-1,2,4-triazole (pyrazole) (3). A plausible mechanism explanation for this rearrangement reaction was presented. It was suggested that the rearrangement reaction could be referred to the thermodynamics transposition leading to the predominant 5-arylureylene-3-benzylthio-1,2,4-triazole energy preferentially.
|
Regioselective addtion of 5-amino-3-benzylthio-l,2,4-triazole and its analogues with aryl isocyanates |
| |
| LU,Rong-Jian QIAN,Bao-Ying DENG,Hai-Yan YANG,Hua-ZhengNational Key Laboratory of Elemento-Organic Chemistry,Institute of Elemento-Organic Chemistry,Nankai University,Tianjin ,China.Regioselective addtion of 5-amino-3-benzylthio-l,2,4-triazole and its analogues with aryl isocyanates[J].Chinese Journal of Chemistry,1997(6). |
| |
| Authors: | LU Rong-Jian QIAN Bao-Ying DENG Hai-Yan YANG Hua-ZhengNational Key Laboratory of Elemento-Organic Chemistry |
| |
| Institution: | LU,Rong-Jian QIAN,Bao-Ying DENG,Hai-Yan YANG,Hua-ZhengNational Key Laboratory of Elemento-Organic Chemistry,Institute of Elemento-Organic Chemistry,Nankai University,Tianjin 300071,China |
| |
| Abstract: | The orientation of the addition of 5-amino-3-benzylthio-1,2,4-triazole and its analogues (pyrazole) (1) with the aryl isocyanate can be directed by controlling the reaction temperature and one of the product, 5-amino-1-arylaminocarbonyl-3-benzylthio-1,2,4-triazole (pyrazole) (2), can rearrange at 170C to another product, 5-arylureylene-3-benzylthio-1,2,4-triazole (pyrazole) (3). A plausible mechanism explanation for this rearrangement reaction was presented. It was suggested that the rearrangement reaction could be referred to the thermodynamics transposition leading to the predominant 5-arylureylene-3-benzylthio-1,2,4-triazole energy preferentially. |
| |
| Keywords: | 1 2 4-Triazole ary isocyanate rearrangement addition reaction |
| 本文献已被 CNKI 等数据库收录！ |
|
