Enantioselective synthesis of allylic alcohols by the sequential aminoxylation-olefination reactions of aldehydes under ambient conditions |
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Authors: | Zhong Guofu Yu Yongping |
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Institution: | Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA. gzhong@scripps.edu |
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Abstract: | A novel, highly enantioselective synthesis of O-amino-substituted allylic alcohols by the sequential asymmetric alpha-aminoxylation/Wadsworth-Emmons-Horner olefination reactions of aldehydes is presented. |
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