Identification of bifucosylated glycoforms using low‐energy CID spectra |
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Authors: | Andrs cs Lilla Turik gnes Rvsz Kroly Vkey Lszl Drahos |
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Institution: | András Ács,Lilla Turiák,Ágnes Révész,Károly Vékey,László Drahos |
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Abstract: | We have used tandem mass spectrometry (MS/MS)‐based analysis of glycopeptides in order to identify the composition and structure of rare glycoforms. The results illustrate utility of low‐energy MS/MS for structure identification. We have shown the presence of bifucosylated and trifucosylated glycoforms in human α‐1‐acid glycoprotein (AGP), a major plasma glycoprotein. Fucosylation in the case of AGP always occurs on the antennae; core fucosylation was not observed. |
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Keywords: | fucosylation glycopeptide glycosylation low‐energy CID |
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