Analysis of methyldopa in the presence of phenylephrine using electrocatalytic effect of a ferrocene derivative at a surface of feather like La3+/ZnO nano‐flowers modified carbon paste electrode

The purpose of the present study was to introduce a newly designed approach for simultaneous determination of methyldopa and phenylephrine using modified carbon paste electrode with feather like La³⁺/ZnO nano‐flowers and N‐(ferrocenylmethylidene) fluoren‐2‐amine (La³⁺/ZnONFMF2ACPE). According to the results from the electrochemical experiments, oxidation current of methyldopa on the modified electrode surface was incremented and its oxidation occurred at a potential about 110 mV less positive than that of an unmodified carbon paste electrode. A linear response was observed for the electrode at different methyldopa concentrations (0.2 to 500.0 μM). The existence of phenylephrine did not induce any change in the modified electrode sensitivity to methyldopa, indicating that they could be measured simultaneously or independently. Real human body samples were used to test our technique efficacy in detecting methyldopa and phenylephrine.