| 新型双腙基喹唑啉类衍生物的合成及其抑菌活性 |
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| 引用本文： | 安锐,熊启中,高元磊,韩菲菲,鲍小平. 新型双腙基喹唑啉类衍生物的合成及其抑菌活性[J]. 合成化学, 2011, 19(6): 699-704 |
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| 作者姓名： | 安锐 熊启中 高元磊 韩菲菲 鲍小平 |
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| 作者单位： | 贵州大学精细化工研究开发中心教育部绿色农药与农业生物工程重点实验室,贵州贵阳,550025 |
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| 基金项目： | 教育部科学技术研究重点项目(209110); 贵州省农业攻关项目(20093010) |
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| 摘 要： | 以邻氨基苯甲酸为起始原料,设计并合成了17个新型的双腙基喹唑啉类衍生物,其结构经1H NMR,13C NMR,IR,MS和元素分析表征.初步生物活性测试结果表明,部分化合物对小麦赤霉菌、辣椒枯萎菌和苹果腐烂菌有一定的抑制活性.
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| 关 键 词： | 喹唑啉 腙 合成 抑菌活性 |
Synthesis and Fungicidal Activities of Novel Dihydrazonyl-quinazoline Derivatives |
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| AN Rui,XIONG Qi-zhong,GAO Yuan-lei,HAN Fei-fei,BAO Xiao-ping. Synthesis and Fungicidal Activities of Novel Dihydrazonyl-quinazoline Derivatives[J]. Chinese Journal of Synthetic Chemistry, 2011, 19(6): 699-704 |
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| Authors: | AN Rui XIONG Qi-zhong GAO Yuan-lei HAN Fei-fei BAO Xiao-ping |
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| Affiliation: | AN Rui,XIONG Qi-zhong,GAO Yuan-lei,HAN Fei-fei,BAO Xiao-ping(Key Laboratory of Green Pesticide and Agricultural Bioengineering,Ministry of Education,Center for Research and Development of Fine Chemicals,Guizhou University,Guiyang 550025,China) |
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| Abstract: | Seventeen novel dihydrazonylquinazoline derivatives were designed and synthesized using o-aminobenzoic acid as the starting material.Their structures were characterized by 1H NMR,13C NMR,IR,MS and elemental analysis.Preliminary bioassay indicated that some compounds exhibited certain fungicidal activities against the Gibberella zeae,Fusarium oxysporum and Cytospora mandshurica. |
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| Keywords: | quinazoline hydrazone synthesis fungicidal activity |
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