Reduction of an asymmetric Pt(IV) prodrug fac-[Pt(dach)Cl3(OC(=O)CH3)] by biological thiol compounds: kinetic and mechanistic characterizations |
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| Authors: | Wang Yafang Ma Dongying Sun Jingjing Song Changying Huo Shuying |
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| Institution: | 1.College of Chemistry and Environmental Science, Key Laboratory of Analytical Science and Technology of Hebei Province, and MOE Key Laboratory of Medicinal Chemistry and Molecular Diagnostics, Hebei University, Baoding, 071002, Hebei Province, People’s Republic of China
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| Abstract: | Transition Metal Chemistry - An asymmetric Pt(IV) prodrug fac-Pt (dach)Cl3(OC(=O)CH3)] (dach?=?1,2-diaminocyclohexane) was synthesized, and the reduction of the Pt(IV) prodrug by three... |
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