Enantiomeric resolution of anti-HIV agents on a cellulose derivative chiral stationary phase |
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| Authors: | Ficarra P. Ficarra R. Chimirri A. Romeo G. Tommasini S. Calabrò M. L. Costantino D. Monforte A. M. Carulli M. |
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| Affiliation: | (1) Dipartimento Farmaco-Chimico, Università di Messina, viale Annunziata, 98168 Messina, Italy;(2) Facoltà di Farmacia, Università di Reggio Calabria, Complesso !["ldquo"]("/content/7077v2k03n6533ru/xlarge8220.gif") Barbieri!["rdquo"]("/content/7077v2k03n6533ru/xlarge8221.gif") , 88021 Roccelletta di Borgia (CZ), Italy |
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| Abstract: | Summary Anti-HIV enantiomeric 1H, 3H-thiazolo[3, 4-a] benzimidazoles have been stereospecifically analyzed by elution on a column of cellulose tris-(4-methyl-phenylbenzoate)ester adsorbed on macroporous silica (ChiralcelR OJ).The enantiomeric resolution of the compounds examined is linked to a complex and competitive contribution of different factors. |
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| Keywords: | Column liquid chromatography Enantio separation ChiralcelR OJ Anti-HIV agents |
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