Long range correlation of hydrophilicity and flexibility along the calcium binding protein chains |
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Authors: | Dana Craciun Adriana Isvoran NM Avram |
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Institution: | a West University of Timisoara, Teacher Training Department, 4 Blvd. V. Parvan, Timisoara 300223, Romania b West University of Timisoara, Department of Chemistry, 16 Pestalozzi, Timisoara 300115, Romania c Nicholas Georgescu-Roegen Interdisciplinary Research and Formation Platform, 16 Pestalozzi, Timisoara 300115, Romania d West University of Timisoara, Department of Physics, 4 Blvd. V. Parvan, Timisoara 300223, Romania e Academy of Romanian Scientists, 54 Independentei Street, Bucharest 050094, Romania |
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Abstract: | Long range correlation concerning hydrophilicity and flexibility along a number of 80 calcium binding protein sequences is confirmed by using spectral analysis and detrended fluctuations analysis methods, as well as by Hurst exponent calculations. There are no significant differences between the correlation properties concerning these properties for the two structural subfamilies, extended and compact, of the calcium binding proteins and they are also similar with the correlation properties revealed by other investigated proteins. This result sustains the hypothesis that the long range correlation of hydrophilicity and flexibility along the chain is a common feature of proteins. |
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Keywords: | Long range correlation Hydrophilicity Flexibility Temperature factor Calcium binding proteins |
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