Imidazole‐coordinated monodentate NHC–Pd(II) complex derived from proline and its application to the coupling reaction of arylboronic acids with carboxylic acid anhydrides in water at room temperature |
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| Authors: | Xiao‐Bao Shen Ting‐Ting Gao Jian‐Mei Lu Li‐Xiong Shao |
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| Institution: | College of Chemistry and Materials Engineering, Wenzhou University, Chashan University Town, Wenzhou, Zhejiang Province 325035, People's Republic of China |
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| Abstract: | Cleavage of a C? N bond of imidazolium salt derived from N‐phenyl‐substituted proline was observed in this laboratory. A novel imidazole‐coordinated monodentate NHC–Pd(II) complex 5 was obtained as the sole product in good yield in the reaction of imidazolium salt 4 with Pd(OAc)2 in refluxing THF. The structure of complex 5 was determined unambiguously by an X‐ray diffraction. The complex was found to be a good catalyst in the cross‐coupling reaction of arylboronic acids with carboxylic acid anhydrides in water at room temperature. Copyright © 2011 John Wiley & Sons, Ltd. |
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| Keywords: | N‐heterocyclic carbene proline palladium coupling reaction synthetic methods |
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