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Z‐DNA Recognition in B‐Z‐B Sequences by a Cationic Zinc Porphyrin |
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| Authors: | Dr Alessandro D'Urso Prof Dr Andrea E Holmes Prof Dr Nina Berova Prof Dr Milan Balaz Prof Dr Roberto Purrello |
| Institution: | 1. Dipartimento di Scienze Chimiche, Università di Catania, Viale A. Doria 6, 95125 Catania (Italy), Fax: (+39)?095‐580138;2. Department of Chemistry, University of Wyoming, 1000 E. University Ave, Laramie, WY 82071 (USA);3. Department of Chemistry, Doane College, 1014 Boswell Ave, Crete, NE (USA);4. Department of Chemistry, Columbia University, 3000 Broadway, New York, NY 10027 (USA) |
| Abstract: | For the first time it has been shown by spectroscopic studies such as circular dichroism and UV/Vis that cationic zinc porphyrin serves as a selective spectroscopic sensor that is able to recognize short left‐handed Z‐DNA tracts embedded in the B‐Z‐B sequences. |
| Keywords: | chiroptical probes circular dichroism DNA recognition porphyrinoids sensors |