The synthesis,crystal structures and antimicrobial studies of C‐methyl‐substituted hexaaza macrocycle of Cu(II) having aromatic pendant arm |
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Authors: | Ahmad Husain Shahab A A Nami K S Siddiqi |
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Institution: | 1. Department of Chemistry, Aligarh Muslim University, Aligarh 202002, India;2. Department of Kulliyat, Faculty of Unani Medicine, Aligarh Muslim University, Aligarh 202002, India;3. Email:ahmad.chem786@hotmail.com, ks_siddiqi@yahoo.co.in |
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Abstract: | Cu(II) complexes of 14‐membered hexaaza macrocyclic ligand with C‐methyl substituent of the type CuL](X)2 (where L = 3,10‐bisbenzyl‐6,13‐dimethyl‐1,3,5,8,10,12‐hexaazacyclotetradecane, and X = ClO4−, PF6−) were synthesized by tandem reaction. They were characterized by spectral and single‐crystal X‐ray diffraction techniques. The complexes show distorted octahedral geometry and the counter ions are weakly coordinated to the metal ion at the axial positions. The macrocyclic ring adopts the trans‐III configuration with six‐ and five‐membered chelate rings in chair and gauche conformation, respectively. It was observed that in the solid state the arrangement of the coordination sphere is distorted octahedral whereas, in solution, a square‐planar structure is predominant. The molar conductance of the complexes indicates that the axially bonded anions are almost dissociated in acetonitrile solution. The Electron Paramagnetic Resonance (EPR) spectrum of complex 1 is axial and consistent with a dx2 − y2 ground state. The CuL](ClO4)2 was found to be active against the tested microorganism. Copyright © 2011 John Wiley & Sons, Ltd. |
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Keywords: | crystal structure macrocycle C‐methyl substituted hydrogen bonding octahedral geometry antifungal and antibacterial activity |
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