Thermal analysis of protein behavior |
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Authors: | R.P. Mcknight F.E. Karasz |
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Affiliation: | Polymer Science and Engineering, University of Massachusetts, Amherst, Mass. 01002 U.S.A. |
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Abstract: | The measurement and significance of heats associated with conformational transitions in solvated proteins and their synthetic analogues are discussed. An outline is given of the principles underlying several calorimetric and non-calorimetric techniques. Some new quantitative results relating to the denaturation of the protein lysozyme, obtained with a modified commercial differential scanning calorimeter, are presented. |
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