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Eco‐friendly and Efficient Synthesis of 2,3‐Dihydroquinazolin‐4(1H)‐ones |
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| Authors: | Ghashang Majid Azizi Kobra Moulavi‐Pordanjani Hamed Shaterian Hamid Reza |
| Affiliation: | Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, PO Box 98135‐674, Zahedan, Iran |
| Abstract: | A simple and facile method for the synthesis of 2,3‐dihydroquinazolin‐4(1H)‐ones through the direct cyclocondensation of one‐pot three‐component cyclocondensation of isatoic anhydride, ammonium acetate (or primary amines) and aldehydes; and anthranilamide and aldehydes using silica supported ferric chloride (SiO2‐FeCl3) as catalyst under solvent‐free conditions is described. |
| Keywords: | solvent‐free synthetic methods aldehydes 2,3‐dihydroquinazolin‐4(1H)‐one anthranilamide isatoic anhydride |