Applications of transition metal complexes containing aminophosphine ligand to transfer hydrogenation of ketones |
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Authors: | Murat Aydemir Akın Baysal Yılmaz Turgut |
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Institution: | Dicle University, Department of Chemistry, TR‐21280 Diyarbak?r, Turkey |
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Abstract: | Hydrogen transfer reduction processes are attracting increasing interest from synthetic chemists in view of their operational simplicity. Reaction of Ph2PNHCH2‐C4H3S] with Ru(η6‐benzene)(µ‐Cl)Cl]2, Rh(µ‐Cl)(cod)]2 and Ir(η5‐C5Me5)(µ‐Cl)Cl]2 gave a range of new monodendate complexes Ru(Ph2PNHCH2‐C4H3S)(η6‐benzene)Cl2], 1, Rh(Ph2PNHCH2‐C4H3S)(cod)Cl], 2, and Ir(Ph2PNHCH2‐C4H3S)(η5‐C5Me5)Cl2], 3, respectively. All new complexes were fully characterized by analytical and spectroscopic methods. 1H? 31P NMR, 1H? 13C HETCOR or 1H? 1H COSY correlation experiments were used to confirm the spectral assignments. 1–3 are suitable catalyst precursors for the transfer hydrogenation of acetophenone derivatives. Notably Ru(Ph2PNHCH2‐C4H3S)(η6‐benzene)Cl2], 1, acts as an excellent catalyst, giving the corresponding alcohols in 98–99% yields in 30 min at 82 °C (TOF ≤200 h?1) for the transfer hydrogenation reaction in comparison to analogous rhodium or iridium complexes. This transfer hydrogenation is characterized by low reversibility under these conditions. Copyright © 2011 John Wiley & Sons, Ltd. |
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Keywords: | aminophosphine transition metals transfer hydrogenation catalysis |
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