Reaction of secondary amines with acetylenic γ-hydroxyaldehydes and γ-ketoacetals |
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Authors: | Medvedeva A. S. Safronova L. P. Kalikhman I. D. Voronkov M. G. |
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Affiliation: | 1.Irkutsk Institute of Organic Chemistry, Siberian Branch of the Academy of Sciences of the USSR, USSR ; |
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Abstract: | 1. | The reaction of acetylenic -hydroxyaldehydes with secondary amines in a methanolic medium leads to the formation of 2-methoxy-4-dialkylamino-5,5-dialkyldihydrofurans. | 2. | Protection of the hydroxyl group in the acetylenic -hydroxyketones allows one to add diethylamine and obtain previously unknown enamines. |
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