Abstract: | By the interaction of substituted chloropyrimidines with the sodium salts of oximes of aliphatic and alicyclic ketoximes, series of O-(4,6-dimethyl-2-pyrimidinyl)- and O-(2,4-dimethyl-6-pyrimidyl)ketoximes have been obtained. Through reactions of 2-methyl-4,6-dichloropyrimidine with salts of ketoximes, the corresponding monosubstituted and disubstituted products have been synthesized. The biological activities of the synthesized substances have been investigated.Erevan Institute of the National Economy, Erevan 375025. M. V. Lomonosov Moscow State University, Moscow 119899. Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 7, pp. 950–956, July, 1997. |