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Cu-catalyzed oxidation of indoles to isatins
Authors:Junfei Luo  Yanchao Zhao  Xing Xu  Junliang Zheng  Hongze Liang
Affiliation:School of Materials Science and Chemical Engineering, Ningbo University, Ningbo 315211, China
Abstract:The first example of Cu-catalyzed oxidation of indoles to isatin derivatives by the use of cheap aqueous tert-butyl peroxide as an oxidant was developed. This methodology is practically convenient and highly functional group tolerant, allowing a variety of indole derivatives to transform into the corresponding isatin derivatives in good yields.
Keywords:Cu-catalyzed  Indoles  Isatin derivatives  Oxidation
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