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Efficient radiosynthesis of a [18F]-phosphonium salt containing closo-carborane |
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| Authors: | Joseph A. Ioppolo Nicolas Giboureau Mohan Bhadbhade Daniel E. Morrison Michael Kassiou Louis M. Rendina |
| Affiliation: | 1. School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia;2. Brain and Mind Centre, The University of Sydney, NSW 2050, Australia;3. Solid State and Elemental Analysis Unit, The University of New South Wales, Kensington, NSW 2052, Australia |
| Abstract: | An efficient synthesis of an 18F-labelled phosphonium salt containing closo-carborane is described. The preparation of this salt was attempted using both single-step and two-step protocols, with greater success found for the latter. An X-ray structure for the unlabelled 19F salt is also presented. |
| Keywords: | Carborane PET imaging Radiolabelling Fluorine-18 |
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