Solid-phase synthesis of imidazo[1,2-a]pyridines and imidazo[1,2-a]pyrimidines |
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| Institution: | a Institut de Chimie Organique et Analytique, UMR CNRS 6005, Université d'Orléans, B.P. 6759, 45067 Orléans Cedex 2, France
b Faculté des Sciences et Techniques de Beni-Mellal, Université Caddi-Ayyad, BP 523, 23000 Beni-Mellal, Maroc |
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| Abstract: | The synthesis of imidazo1,2-a]pyridine and imidazo1,2-a]pyrimidine derivatives by condensation between an α-bromoketone bound to solid support and various 2-aminopyridine or 2-aminopyrimidine derivatives was described. Either an acid labile linker or a base labile linker was used in this study. |
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