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Studies on novel macrocyclization methods of cembrane-type diterpenoids: a Stille cyclization approach to (±)-isocembrene
Authors:Lizeng PengFengzhi Zhang  Tiansheng MeiTao Zhang  Yulin Li
Institution:National Laboratory of Applied Organic Chemistry, Institute of Organic Chemistry, Lanzhou University, Lanzhou 730000, PR China
Abstract:An efficient total synthesis of (±)-isocembrene via an intramolecular Stille cross-coupling reaction is described. A novel strategy towards the 1,3-diene-based cembrane-type macrocyclic diterpenoids has been realized.
Keywords:isocembrene  diterpenoids  cembranoids  Stille reaction
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