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Synthesis of Δ-pyrrolines and Δ-tetrahydropyridines via microwave-accelerated ring-closing metathesis |
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| Authors: | Ronald Grigg William MartinJames Morris Visuvanthar Sridharan |
| Affiliation: | a Molecular Innovation, Diversity and Automated Synthesis (MIDAS) Centre, School of Chemistry, Leeds University, Leeds LS2 9JT, UK b Process Research and Development, GlaxoSmithKline, Stevenage SG1 2NY, UK |
| Abstract: | Microwave irradiation effects ring-closing metathesis of electron-deficient and sterically conjested double bonds with a drastic reduction in reaction time and reduced catalyst loading. |
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