Amberlite IR-120 catalysed efficient synthesis of glycosyl enamines and their application |
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| Authors: | Neetu TewariDiksha Katiyar Vinod K TiwariRama P Tripathi |
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| Institution: | Division of Medicinal Chemistry, Central Drug Research Institute, Lucknow 226001, India |
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| Abstract: | β-Keto esters and acetyl acetone on condensation with glycosylated amino esters in the presence of IR-120 resin resulted in high yields of glycosyl enamino esters or ketones. The latter on cyclisation with NaH in toluene at reflux gave 6-glycosyl-5,6-dihydro-1H-pyridin-4-ones in fair to good yields. |
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