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Highly efficient synthesis of buflavine: a unique Amaryllidaceae alkaloid |
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| Authors: | Poolsak SahakitpichanSomsak Ruchirawat |
| Affiliation: | a Chulabhorn Research Institute, Vipavadee Rangsit Highway, Bangkok 10210, Thailand b Department of Chemistry, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand c Chulabhorn Research Centre, Institute of Science and Technology for Research and Development, Mahidol University, Salaya Campus, Thailand |
| Abstract: | The Amaryllidaceae alkaloid buflavine 1 has been synthesized in three steps by Suzuki-Miyaura cross coupling, reduction and the cascade reactions of Pictet-Spengler type and Eschweiler-Clarke N-methylation. |
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