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Conversion of naringenin and hesperetin by heterogeneous catalytic Baeyer-Villiger reaction into lactones exhibiting apoptotic activity |
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| Authors: | Roberta Bernini Enrico MincioneManuela Cortese Raffaele SaladinoGiampiero Gualandi Maria Cristina Belfiore |
| Affiliation: | a Organic Chemistry, Dipartimento ABAC, Università degli Studi della Tuscia, Via S. Camillo De Lellis, 01100 Viterbo, Italy b Genetic of Microorganisms, Dipartimento ABAC, Università degli Studi della Tuscia, Via S. Camillo De Lellis, 01100 Viterbo, Italy |
| Abstract: | Naringenin and hesperetin were converted into the corresponding lactones by hydrogen peroxide activated by poly(4-vinylpiridine)-supported methyltrioxorhenium in t-butanol, an environmentally friendly catalytic system. The products showed a marked apoptotic activity in the genetic tests. |
| Keywords: | naringenin hesperetin Baeyer-Villiger reaction heterogeneous catalysis |
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