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Asymmetric synthesis of the erythrinan alkaloid system using a chiral lithium amide base desymmetrisation as the key step
Authors:Christopher GillDaniel A Greenhalgh  Nigel S Simpkins
Institution:School of Chemistry, The University of Nottingham, University Park, Nottingham NG7 2RD, UK
Abstract:A new asymmetric approach to the erythrinan alkaloid system is described, which involves chiral base desymmetrisation of a ring fused imide and a 6-exo-trig radical cyclisation as the key steps.
Keywords:chiral lithium amide base  erythrinan alkaloid  radical cyclisation
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