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An easy approach for the acetylation of saccharidic alcohols. Applicability for regioselective protections
Authors:Matteo AdinolfiGaspare Barone  Alfonso Iadonisi  Marialuisa Schiattarella
Affiliation:Dipartimento di Chimica Organica e Biochimica, Università degli Studi di Napoli Federico II, Via Cynthia 4, I-80126 Napoli, Italy
Abstract:Cheap 4 Å molecular sieves can promote acetylation of carbohydrate hydroxyl functions with Ac2O in absence of any co-reagent. The procedure is compatible with the presence of a variety of acid labile protecting groups and can be exploited for regioselective protections.
Keywords:carbohydrates   protecting groups   acetylation   regioselectivity   molecular sieves
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