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The Synthesis of 2‐(Chromon‐2/3‐yl)‐3‐(5‐thione‐4‐hydro‐1,3,4‐thiadiazol‐2‐yl)‐4‐oxo‐thiazolidine
Authors:Gui‐Hua Yang  Ling‐Hua Cao  Peng‐Yuan Cui
Abstract:2‐Formylchromones and 3‐formylchromones as the first materials singly reacted with 2‐amino‐5‐mercapto‐1,3,4‐thiadiazole to give the corresponding Schiff bases, which on cyclocondensation with mercapto‐acetic acid in 1,4‐dioxane yielded target compounds named 4‐oxo‐thiazolidines. The structures of all the synthetic compounds were confirmed by elemental analysis and IR, 1H NMR, LC‐MS (ESI) spectral data.
Keywords:Formylchromone  Schiff base  2‐Amino‐5‐mercapto‐1  3  4‐thiadiazole  4‐Oxo‐thiazolidine  Synthesis
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