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A facility for the production of iodine-123 by spallation of caesium |
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| Authors: | J S Vincent A H Dougan D L Lyster J W Blue |
| Institution: | (1) Triumf University of British Columbia, Vancouver, B.C., (Canada);(2) Department of Pharmaceutical Sciences, University of British Columbia, Vancouver, B. C., (Canada);(3) NASA-Lewis Research Centre, Cleveland, Ohio, (USA) |
| Abstract: | A facility for the continuous production of iodine-123 by spallation of elemental caesium by 482 MeV protons has been in operation at a TRIUMF beam dump for about 2 years. Radioxenon from the target is efficiently trapped on alumina which is subsequently used to remove the121Te decay product. The yield is 100 mCi/h from a 20 gm/cm2 target at 10 μA. Impurities are125I<2% and121Te<0.2% at 27 hours after end of production. The123I consists mainly of iodide along with significant iodate impurity. The product is used extensively in Canadian clinics for thyroid analyses and for labelling radiopharmaceuticals. |
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